GILTERITINIB: A NOVEL FLT3 INHIBITOR FOR ACUTE MYELOID LEUKEMIA

Gilteritinib: a novel FLT3 inhibitor for acute myeloid leukemia

Abstract FMS-like tyrosine kinase 3- internal tandem duplication (FLT3-ITD) remains as one of the most frequently mutated genes in acute myeloid leukemia (AML), especially in those with normal cytogenetics.The FLT3-ITD and FLT3-TKD (tyrosine kinase domain) mutations are biomarkers for high risk AML and are associated with drug resistance Goalie - G

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The Aesthetic of Right. How Historical Fake Feeds Populist Agendas

Fake News as propaganda is not a novel creation by the former President of the United States (POTUS) and the use of architecture as propaganda to propel Hockey Protective - Gloves - Youth populist agendas is no different.This article will observe two case studies, Skopje 2014 implemented by the nationalist conservative party VMRO-DPMNE of Macedonia

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On the pathway of cellular uptake: new insight into the interaction between the cell membrane and very small nanoparticles

For any living cell the exchange with its environment is vital.Therefore, many different kinds of cargo are able to enter cells via energy-dependent or -independent routes.Nanoparticles are no exemption.It is known that small silica nanoparticles with a diameter below 50 nm are taken up by cells and that their uptake exerts pronounced toxic effects

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